BioVis 2011 Abstract
Analysis-Ready Meshes of Neuronal Forests
Construction of spatially realistic models of neuronal processes is an essential step toward meaningful electro-physiological and reaction-diffusion simulations. Many techniques have been developed to replicate the intricate branching of the dendritic arbor of single neuronal processes, but few methods are able to capture the native structures of multiple cells in close proximity, i.e. the 3D structure of neuropil, or a "forest" of structures. In this abstract, we propose criteria for analysis-readiness of a mesh and present a pipeline of methods along with a suite of computational tools to reconstruct, from a stack of serial section transmission electron microscopy (ssTEM) images, surface and volumetric mesh forests that meet these criteria.
BioVis 2011 Papers and Abstracts
